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The product is for non-human research only. Artemisinin is isolated from the plant Artemisia annua.Ī water-soluble, semi-synthetic derivative of the sesquiterpene lactone artemisinin with anti-malarial, anti-schistosomiasis, antiviral, and potential anti-neoplastic activities 384.4 g/molĤ-Oxo-4-hexadecan-10-yl)oxy]butanoic acid Artesunate has also been shown to stimulate cell differentiation, arrest the cell cycle in the G1 and G2/M phases, inhibit cell proliferation, and induce apoptosis through mitochondrial and caspase signaling pathways. Additionally, in vitro studies demonstrate that this agent induces DNA breakage in a dose-dependent manner. Upon hydrolysis of artesunate's active endoperoxide bridge moiety by liberated heme in parasite-infected red blood cells, reactive oxygen species and carbon-centered radicals form, which have been shown to damage and kill parasitic organisms. 4-Oxo-4-hexadecan-10-yl)oxy]butanoic acid Others Artesunate is a water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-schistosomiasis, antiviral, and potential anti-neoplastic activities.
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